Product Description

2'-Fucosyllactose (2'-FL), nrog rau cov npe tshuaj lom neeg CAS#41263-94-9, yog ib qho tshwj xeeb thiab tseem ceeb oligosaccharide uas tau txais kev pom zoo nyob rau xyoo tas los no vim nws cov txiaj ntsig zoo thiab kev siv ntau.

Chemical Structure thiab Properties

2'-FL yog trisaccharide tsim los ntawm lactose thiab fucose molecule txuas rau galactose moiety ntawm lactose ntawm 2' txoj hauj lwm. Nws cov tshuaj formula yog C18H32O15.

Nyob rau hauv cov nqe lus ntawm lub cev muaj zog, 2'-FL yog ib tug dawb mus rau off-dawb hmoov uas yog soluble nyob rau hauv dej. Nws muaj ib tug qab zib saj thiab yog kuj ruaj khov nyob rau hauv ib txwm cia tej yam kev mob. Cov molecule muaj ib qho kev sib hloov ntawm li +120 degree (c=1, dej).

Qhov chaw thiab Biosynthesis

2'-FL yog ib txwm muaj nyob rau hauv tib neeg cov mis nyuj, qhov twg nws yog ib qho ntawm cov oligosaccharides ntau tshaj. Nws yog tsim los ntawm cov qog mammary ntawm cov poj niam lactating los ntawm cov txheej txheem enzymatic complex. Ntxiv rau tib neeg cov mis nyuj, 2'-FL kuj tuaj yeem pom muaj me me hauv qee qhov chaw lom neeg, xws li nyuj cov mis nyuj thiab qee yam nroj tsuag.

Txawm li cas los xij, vim muaj qhov tsis txaus ntawm cov peev txheej ntuj, 2'-FL feem ntau yog tsim los ntawm cov txheej txheem fermentation. Cov txheej txheem tsim khoom siv hluav taws xob suav nrog cov khoom siv tshuaj lom neeg lossis cov khoom siv enzymatic siv cov enzymes tshwj xeeb. Cov txheej txheem fermentation siv genetic engineered kab mob los yog poov xab los tsim 2'-FL.

Cov dej num lom neeg

Kev Ua Haujlwm Prebiotic

Ib qho ntawm cov haujlwm lom neeg tseem ceeb ntawm 2'-FL yog nws cov nyhuv prebiotic. Prebiotics yog cov tshuaj uas tsis yog digestible uas xaiv txhawb kev loj hlob thiab kev ua haujlwm ntawm cov kab mob muaj txiaj ntsig hauv plab. 2'-FL yog xaiv fermented los ntawm cov kab mob tshwj xeeb, xws li bifidobacteria thiab lactobacilli, uas yog ib qho tseem ceeb rau kev noj qab haus huv plab microbiota.

Los ntawm kev txhawb nqa kev loj hlob ntawm cov kab mob no, 2'-FL tuaj yeem pab txhim kho plab hnyuv, txhim kho plab zom mov, thiab ntxiv dag zog rau lub cev.

Anti-Infective Properties

2'-FL kuj tau pom tias muaj cov khoom tiv thaiv kab mob. Nws tuaj yeem khi rau cov kab mob, xws li cov kab mob thiab cov kab mob, thiab tiv thaiv lawv los ntawm kev ua raws li txoj hnyuv epithelium. Qhov no tuaj yeem pab txo qis kev pheej hmoo ntawm kev kis kab mob thiab txhim kho lub cev tiv thaiv kab mob.

Piv txwv li, cov kev tshawb fawb tau pom tias 2'-FL tuaj yeem khi rau qee yam kab mob ntawm cov kab mob E. coli thiab Salmonella, txo lawv lub peev xwm ua rau kis kab mob.

Immune Modulation

2'-FL tuaj yeem hloov kho lub cev tiv thaiv kab mob los ntawm kev cuam tshuam nrog lub cev tiv thaiv kab mob hauv plab. Nws tuaj yeem txhawb kev tsim cov cytokines thiab lwm yam tshuaj tiv thaiv kab mob, uas tuaj yeem txhim kho lub cev tiv thaiv kab mob thiab tiv thaiv kab mob.

Tsis tas li ntawd, 2'-FL kuj tseem tuaj yeem pab tswj qhov sib npaug ntawm cov lus teb rau cov tshuaj tiv thaiv kab mob thiab tiv thaiv kab mob, uas yog qhov tseem ceeb rau kev tswj hwm lub cev tsis muaj zog.

Kev loj hlob ntawm hlwb

Qee qhov kev tshawb fawb qhia tias 2'-FL tuaj yeem ua lub luag haujlwm hauv lub hlwb. Nws tuaj yeem hla cov ntshav-hlwb teeb meem thiab cuam tshuam nrog cov hlwb neural, uas muaj feem cuam tshuam rau kev paub txog kev ua haujlwm thiab kev loj hlob ntawm lub hlwb.

Txawm li cas los xij, xav tau kev tshawb fawb ntxiv kom nkag siab txog qhov cuam tshuam ntawm 2'-FL ntawm kev loj hlob ntawm lub hlwb.

Daim ntawv thov

Me Nyuam Noj Khoom Noj

2'-FL yog siv dav hauv cov menyuam mos mis los ua cov khoom siv ua haujlwm los ua cov txiaj ntsig ntawm tib neeg cov mis nyuj oligosaccharides. Cov mis mos uas muaj 2'-FL tuaj yeem pab txhawb kev loj hlob thiab kev loj hlob ntawm cov menyuam mos los ntawm kev muab cov teebmeem prebiotic, txhawb kev tiv thaiv kab mob, thiab txo cov kev pheej hmoo ntawm kev kis kab mob.

Tsis tas li ntawd, 2'-FL kuj tuaj yeem txhim kho lub palatability thiab digestibility ntawm cov qauv me nyuam mos.

Khoom noj khoom haus thiab dej haus

2'-FL tuaj yeem muab ntxiv rau cov khoom noj khoom haus thiab dej haus kom muaj txiaj ntsig zoo. Piv txwv li, nws tuaj yeem muab tso rau hauv yogurts, kua txiv hmab txiv ntoo, thiab khoom noj khoom haus. Cov khoom noj khoom haus thiab dej haus uas muaj 2'-FL tau dhau los ua neeg nyiam vim cov neeg siv khoom paub ntau ntxiv txog qhov tseem ceeb ntawm lub plab noj qab haus huv thiab kev tiv thaiv kab mob.

Pharmaceuticals

2'-FL tseem tab tom tshawb nrhiav rau nws cov peev txheej hauv kev siv tshuaj. Nws tuaj yeem siv los ua tus neeg xa tshuaj los yog cov khoom siv hauv cov tshuaj rau kev kho mob ntawm qee yam kab mob, xws li kab mob sib kis thiab kev tiv thaiv kab mob.

Txawm li cas los xij, kev tshawb fawb ntxiv yog xav tau los txiav txim siab txog kev nyab xeeb thiab kev ua tau zoo ntawm 2'-FL hauv kev siv tshuaj.

Kev nyab xeeb thiab toxicity

2'-FL feem ntau suav hais tias muaj kev nyab xeeb rau kev noj. Nws yog ib txwm muaj nyob rau hauv tib neeg cov mis nyuj thiab tau noj los ntawm cov menyuam mos rau ntau pua xyoo yam tsis muaj kev cuam tshuam tsis zoo. Synthetic los yog fermented 2'-FL kuj suav hais tias muaj kev nyab xeeb thaum tsim nyob rau hauv kev tsim khoom tsim nyog.

Txawm li cas los xij, ib yam li cov khoom xyaw tshiab, nws yog ib qho tseem ceeb uas yuav tsum tau ua tib zoo ntsuam xyuas kev nyab xeeb kom ntseeg tau tias nws muaj kev nyab xeeb rau tib neeg noj. Qhov no suav nrog kev tshawb fawb txog toxicity, allergenicity, thiab cov teebmeem ntev.

Hauv kev xaus, 2'-fucosylactose (CAS#41263-94-9) yog ib qho tshwj xeeb thiab tseem ceeb oligosaccharide nrog ntau cov txiaj ntsig thiab kev siv. Nws cov haujlwm prebiotic, tiv thaiv kab mob, kev tiv thaiv kab mob, thiab lub luag haujlwm tseem ceeb hauv kev loj hlob ntawm lub hlwb ua rau nws muaj txiaj ntsig zoo hauv cov menyuam mos noj zaub mov, khoom noj khoom haus, thiab tshuaj. Raws li kev tshawb fawb txuas ntxiv nthuav tawm ntau ntxiv txog cov txiaj ntsig ntawm 2'-FL, nws yuav ua lub luag haujlwm tseem ceeb hauv kev txhawb nqa tib neeg kev noj qab haus huv.

2'-Focusllactose Cov ntaub ntawv yooj yim

Khoom npe	2'-Focusllactose
CAS	41263-94-9
MF	C18H32O15
MW	488.44

2'-Focusllactose Cov Khoom Siv Tshuaj

Melting point	230-231 degree (decomp)
Boiling point	9 02.2 ± 65.0 degree (Tshaj tawm)
Qhov ntom	1.548 g / cm3
Solubility	H2O: soluble 2mg + 0.2mL, ntshiab, tsis muaj xim
Daim ntawv	Khoom
Xim	Tawm-dawb mus rau daj daj
Kev ruaj ntseg	Hygroscopic