Gamma Aminobutyric Acid (GABA) CAS # 56-12-2

Gamma Aminobutyric Acid (GABA) CAS # 56-12-2

Khoom npe: Gamma Aminobutyric AcidCAS No.: 56-12-2Synonyms: GABA; 4-Aminobutanoic acid; Gamma-aminobutyric acidMolecular Formula: C4H9NO2Molecular Luj: 103.12Thiab: Dawb crystalline hmoovSpecification: USP, EP, FCC; Cov ntsiab lus ntau dua lossis sib npaug rau 99%
Xa kev nug
Hauj lwm lawm
Product Description

 

Gamma-aminobutyric acid, feem ntau hu ua GABA, nrog rau cov npe tshuaj lom neeg CAS # 56-12-2, yog ib qho tseem ceeb sib xyaw nrog qhov tseem ceeb hauv ntau yam txheej txheem lom neeg thiab muaj peev xwm siv tau hauv ntau qhov chaw.

 

Chemical Structure thiab Properties

 

GABA yog ib qho uas tsis yog -protein amino acid uas muaj plaub -carbon saw nrog ib pawg amino thiab ib pawg carboxyl. Nws cov qauv tshuaj muab nws cov khoom tshwj xeeb uas ua rau nws txawv ntawm lwm cov amino acids.

Hais txog lub cev muaj zog, GABA yog cov hmoov dawb crystalline uas yog soluble hauv dej. Nws muaj qhov melting point ntawm ib ncig ntawm 202-204 degree. GABA kuj ruaj khov nyob rau hauv ib txwm muaj mob tab sis tuaj yeem degraded los ntawm qee cov enzymes thiab tshuaj lom neeg cov tshuaj tiv thaiv.

 

Qhov chaw thiab Biosynthesis

 

GABA yog ib txwm tsim nyob rau hauv tib neeg lub cev thiab nyob rau hauv ntau yam kab mob. Hauv tib neeg lub hlwb, nws yog tsim los ntawm glutamate los ntawm enzyme glutamic acid decarboxylase (GAD). Glutamate yog ib hom kab mob neurotransmitter uas hloov mus rau GABA los ntawm cov tshuaj tiv thaiv enzymatic.

Ntxiv nrog rau kev tsim tawm hauv lub cev, GABA kuj tuaj yeem pom hauv qee yam khoom noj. Cov khoom noj uas muaj GABA muaj xws li cov khoom fermented xws li miso, kua ntses, thiab pickles. Qee cov nroj tsuag kuj muaj me me ntawm GABA.

 

Cov dej num lom neeg

Neurotransmitter muaj nuj nqi

Ib qho ntawm cov luag haujlwm tseem ceeb tshaj plaws ntawm GABA yog raws li ib qho neurotransmitter hauv nruab nrab paj hlwb. Nws ua raws li inhibitory neurotransmitter, txhais tau hais tias nws txo cov kev ua ntawm paj hlwb. Los ntawm inhibiting kev sib kis ntawm cov paj hlwb, GABA pab tswj lub hlwb kev ua si thiab tswj qhov sib npaug ntawm excitation thiab inhibition.

GABA koom nrog ntau lub hlwb ua haujlwm xws li pw tsaug zog, ntxhov siab, teb kev ntxhov siab, thiab cov leeg nqaij. Kev tsis txaus ntawm GABA qib tau cuam tshuam nrog ntau yam kev puas hlwb xws li qaug dab peg, ntxhov siab vim, thiab insomnia.

Txoj Cai Ntshav Siab

GABA tau pom tias muaj ntshav siab- txo qis. Nws tuaj yeem nthuav cov hlab ntsha thiab txo qis peripheral tsis kam, ua rau txo cov ntshav siab. Cov nyhuv no yog xav tias yuav kho kom haum xeeb los ntawm kev ua kom GABA receptors hauv cov hlab ntsha thiab lub paj hlwb.

Kev noj zaub mov nplua nuj hauv GABA lossis ntxiv nrog GABA tau raug npaj ua lub tswv yim zoo rau kev tiv thaiv thiab kho ntshav siab.

Txo kev ntxhov siab

GABA kuj tuaj yeem pab txo kev ntxhov siab thiab ntxhov siab. Los ntawm inhibiting qhov kev ua ntawm hypothalamic{1}}pituitary-adrenal (HPA) axis, uas yog lub luag haujlwm rau cov lus teb kev ntxhov siab, GABA tuaj yeem pab txo qis cortisol thiab txhawb kev nkag siab ntawm kev so.

Qhov kev ntxhov siab no- txo cov txiaj ntsig ntawm GABA tau ua rau nws siv hauv cov khoom noj khoom haus thiab cov khoom noj muaj txiaj ntsig rau kev tswj kev ntxhov siab.

Antioxidant Kev Ua Haujlwm

Qee cov kev tshawb fawb tau qhia tias GABA tuaj yeem muaj cov khoom antioxidant. Nws tuaj yeem tshem tawm cov dawb radicals thiab txo cov kev ntxhov siab oxidative, uas muaj txiaj ntsig zoo rau kev noj qab haus huv tag nrho thiab tuaj yeem pab tiv thaiv ntau yam kab mob.

Txawm li cas los xij, xav tau kev tshawb fawb ntxiv kom nkag siab txog cov tshuaj tiv thaiv kab mob antioxidant ntawm GABA thiab nws cov peev xwm siv tau los tiv thaiv oxidative puas tsuaj.

 

Daim ntawv thov

Khoom noj khoom haus

GABA yog dav muaj raws li kev noj haus ntxiv. Nws yog feem ntau ua lag luam rau nws txoj kev ntxhov siab- txo, tsaug zog- txhawb nqa, thiab ntshav siab- txo qis. Cov tshuaj GABA feem ntau yog muag hauv tshuaj ntsiav, ntsiav tshuaj, lossis hmoov daim ntawv.

Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias qhov ua tau zoo thiab kev nyab xeeb ntawm GABA cov tshuaj yuav txawv nyob ntawm qhov chaw, ntau npaum li cas, thiab qhov sib txawv ntawm tus kheej. Raws li nrog rau ib qho ntxiv, nws raug nquahu kom sab laj tus kws kho mob ua ntej noj cov tshuaj GABA.

Khoom noj khoom haus thiab dej haus

GABA tuaj yeem muab ntxiv rau cov khoom noj thiab dej haus ua haujlwm kom muaj txiaj ntsig kev noj qab haus huv. Piv txwv li, nws tuaj yeem muab tso rau hauv cov tshuaj yej, kua txiv hmab txiv ntoo, thiab khoom noj txom ncauj. Cov khoom no yog tsim los pab cov neeg siv khoom tswj kev ntxhov siab, txhim kho kev pw tsaug zog, thiab tswj cov ntshav siab.

Qhov sib ntxiv ntawm GABA rau cov khoom noj khoom haus thiab dej haus yog qhov sib txawv hauv kev lag luam khoom noj khoom haus vim cov neeg siv khoom txaus siab rau cov khoom xyaw ntuj thiab ua haujlwm.

Pharmaceuticals

GABA tseem raug tshuaj xyuas rau nws cov peev xwm siv hauv cov tshuaj. Nws tuaj yeem tsim los ua ib qho tshuaj rau kev kho mob ntawm cov kab mob neurological xws li qaug dab peg, ntxhov siab vim, thiab insomnia. Tsis tas li ntawd, nws cov ntshav siab- txo qis thiab cov tshuaj tiv thaiv antioxidant tuaj yeem ua rau nws muaj peev xwm sib tw rau kev tiv thaiv thiab kho cov kab mob plawv thiab oxidative kev nyuaj siab- cuam tshuam txog kev puas tsuaj.

Txawm li cas los xij, xav tau kev tshawb fawb ntxiv los txiav txim siab txog kev nyab xeeb thiab kev ua tau zoo ntawm GABA ua tus neeg sawv cev tshuaj.

 

Kev nyab xeeb thiab toxicity

 

Feem ntau, GABA suav hais tias muaj kev nyab xeeb thaum noj hauv qhov tsim nyog. Txawm li cas los xij, koob tshuaj GABA ntau yuav ua rau muaj kev phiv xws li qaug zog, kiv taub hau, thiab xeev siab. Cov neeg uas muaj qee yam mob xws li kab mob siab lossis kab mob raum yuav tsum tau ceev faj thaum noj cov tshuaj GABA.

Raws li nrog rau cov tshuaj ntxiv lossis tshuaj, nws yog ib qho tseem ceeb uas yuav tsum tau ua raws li cov lus pom zoo thiab sab laj nrog kws kho mob yog tias koj muaj kev txhawj xeeb lossis mob hauv qab.

Hauv kev xaus, gamma-aminobutyric acid (GABA) yog ib qho kev sib xyaw ua ke nrog cov dej num tseem ceeb lom neeg thiab muaj peev xwm siv tau. Nws lub luag haujlwm ua cov tshuaj neurotransmitter, tswj ntshav siab, txo kev ntxhov siab, thiab antioxidant ua rau nws lub hom phiaj tseem ceeb rau kev tshawb fawb thiab kev loj hlob hauv kev noj qab haus huv thiab khoom noj khoom haus. Txawm hais tias yog kev noj zaub mov ntxiv, cov khoom noj muaj txiaj ntsig, lossis tus neeg sawv cev tshuaj, GABA tuav cov lus cog tseg rau kev txhim kho tib neeg kev noj qab haus huv thiab kev noj qab haus huv-. Txawm li cas los xij, kev tshawb fawb ntxiv yog xav tau kom nkag siab tag nrho nws cov txheej txheem ntawm kev ua thiab kev pheej hmoo.

 

GABA Basic information

 

Khoom npe

Gamma{0}}Aminobutyric acid

CAS

56-12-2

MF

C4H9 NPO 2

MW

103.12

EINECS

200-258-6

 

4-Aminobutyric acid Cov Khoom Siv Tshuaj

 

Melting point

195℃(lub kaum hli ntuj) (lit.)

Boiling point

248.0 ± 23.0℃(Tshaj tawm)

Qhov ntom

1.2300 (kwv yees)

Refractive Index

1.4650 (kwv yees)

Solubility

H2O: 1 M ntawm 20 degree, ntshiab, tsis muaj xim

Daim ntawv

Hmoov

Xim

Dawb mus yuav luag dawb

tsw

Ntawm 1.00% hauv propylene glycol. savory meaty

Hom tshuaj tsw qab

Nqaij

Dej Solubility

SOLUBLE

Yog tias koj txaus siab rau peb Gamma Aminobutyric Acid lossis muaj lus nug, thov koj xav tiv tauj peb. Peb tos ntsoov yuav tau txais koj qhov kev nug thiab tsim kom muaj sijhawm ntev - thiab kev sib raug zoo nrog koj! Hu rau peb: Email: sales@huarongpharma.com, WhatsApp: +86 13751168070

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