Cov Khoom Siv Khoom Siv Khoom
| Yam | Cov ntsiab lus |
|---|---|
| Khoom npe | Kev ua si acid |
| Cas Tsis tau. | 1197-18-8 |
| Txhais lus hais tias | Trans-4- (Aminomethyl) Cyclohexanianecarboxylic acid; Amcha; CykLokapron® (hom npe rau cov kev ntsuas hemostasis); Lysteda® (Hom npe rau ntawm Menorhagia) |
| Molecular Cov Qauv | C₈h₁₅no₂ |
| Molecular hnyav | 157.21 |
| Kev tshwm sim | Dawb lossis yuav luag dawb crystalline hmoov; Tsw |
| Kev qhia tshwj xeeb | - Kws Tshuaj Ntsuam Xyuas: Purity ntau dua los yog sib npaug rau 99.0% (HPLC); pH (5% kev daws teeb meem) 6.0 - 8.0; Poob rau ziab qis dua lossis sib npaug rau 0.5%; Residue ntawm ignition tsawg dua los yog sib npaug rau 0.1%; Cov hlau hnyav (PB tsawg dua lossis sib npaug rau 10ppm, Hg tsawg dua lossis sib npaug ntawm 1PPM, CD tsawg dua lossis sib npaug lossis sib npaug); Chloride (CLT) tsawg dua lossis sib npaug rau 0.02% -Qib rau Qib Cosmetic: Purity ntau dua los yog sib npaug rau 98.0% (HPLC); Ua raws li Inci (International nomenclature ntawm cov tshuaj pleev ib ce) cov qauv |
| Melting taw tes | 233-237 Qib (Nrog Decomposition) |
| So | Dawb soluble hauv dej (ntau dua lossis sib npaug rau 100 g / l ntawm 25 degree); Me ntsis soluble hauv methanol; Insoluble hauv ethanol, acetone, thiab chloroform |
| Kev Cia | Khaws rau hauv qhov txias (15 {- 25 degree), qhuav, lub teeb-tiv thaiv lub thawv; Ntim los tiv thaiv kev nqus dej noo; Txee Lub Neej: 36 lub hlis rau cov qhabnuveutical, 24 lub hlis rau qib Cosmetic |
Core Functions & Cov Ntawv Thov
Tranexamic acid exertts nws cov txuj ci tseem ceeb ntawm kev sib tw ntawm plasminogen ua rau plasminogen ua rau plasmin (cov enzyme uas degrades fibrin txhaws). Qhov no khaws cia cov ntshav txhaws uas twb muaj lawm thiab txo cov fibrinolysis (thawb rhuav tshem), yog li tswj kev los ntshav. Hauv cov tshuaj pleev ib ce, nws tiv thaiv melanin synthesis los ntawm suppressing tyrosinase kev ua si thiab Melanocyte kev ua kom tiav. Nws yog tshwj xeeb siv nyob rau hauvCov Khoom Siv Tib Neeg thiab Cov Khoom Siv Kho Mob(Tsis muaj cov khoom siv tsiaj) nyob ntawm thaj chaw tseem ceeb:
1. Kws ua teb (hemorrhage tswj & hemostatic txoj kev kho)
1.1 gynecological & obstetric hemorrhage
Los ntshav (menorrhagia): Thawj {- kab kab rau idiopathic menorrhagiab ntau dua lossis sib npaug rau cov poj niam prepenopausal. Txo cov cev ntas los ntawm 30-50% nyob rau hauv 1-2 voj voog los ntawm stabilizing kev ua kom cov ntshav ua kom khov kho. Cov tshuaj txheem txheem: 1-1.5 g gyally, 3 zaug txhua hnub thaum coj khaub ncaws (rau 3-5 hnub).
Postpartum hemorrhage (pph): Siv raws li qhov thib ob - kab tus neeg sawv cev rau pph tsis teb rau uterotonics (piv txwv li, oxytocin). Muab raws li kev txhawb nqa (IV) Txoj kev pheej hmoo (1 g tshaj li 8 teev) los txo kev pheej hmoo ntawm 8 teev los ntawm kev ua haujlwm ntawm Uterine atony lossis Placental Aony.
1.2 Kev phais mob hemorrhage
Mob plawv, orthopedic, & phais hniav: Muaj kev tiv thaiv prolascactically los txo perioperative los ntshav thiab hloov kho qhov tseev kom muaj. Piv txwv li:
Kev phais mob cardoC: IV Txoj kev lis ntshav ntawm 10-20 ua ntej daim tawv nqaij phais, ua raws li 10 mg / kg txhua 6 teev rau 24 teev.
Kev rho nyiaj hniav (hauv cov neeg mob hemophilia): qhov ncauj ntawm 1 {}} 1. Tom qab 1-3 hnub los tiv thaiv tom qab-extraction ntshav.
Kev Mob Siab -} cuam tshuam hemorrhage: Muaj nyob rau hauv kev puas tsuaj tswj kev rov ua haujlwm rau kev raug mob hnyav (piv txwv li, blunt plab kev raug mob, pelvic pob txha caj dab (pelvic pob txha nqaj) kom txo qis fibrinoly- induced coagulopathy. IV Koobhuve: 1 g thauj khoom, ua raws li 1 g tshaj 8 teev (yog los ntshav tawm tsam).
1.3 Lwm cov hemorrhagic tsis zoo
Hemophilia A / B & Von Consebrant mob: Kev kho kom haum rau kev kho mob kho mob (Frt) kom txhim kho cov hemostasis thaum los ntshav tawm tsam (piv txwv li ntshav), mucosal los ntshav). Qhov ncauj lossis IV kev tswj hwm txo cov tshuaj lim dej thiab sijhawm ntev.
Melena & Hematemesis (lub plab zom mov los ntshav): Siv hauv cov neeg mob peptic Ulcer los ntshav lossis esophagy vixen los ntshav (tom qab endoscopic hemostasis) los tiv thaiv kev txhawb nqa. IV Txoj kev lis ntshav ntawm 1 g txhua 6 teev rau 5 hnub txo kev pheej hmoo rov qab los ntawm ~ 20%.
2. Kev kom zoo nkauj (hyperpigmentation tswj)
Melasma & chloasma: Ib Kub {{0} Tus qauv tshuaj ntsuab hauv kev kho cov tshuaj haminding (piv txwv li ntawm cev xeeb tub {{{5 {5 {5} {5} {5} {5} Nws tiv thaiv melanin ntau lawm los ntawm:
Thaiv kev sib cuam tshuam ntawm Melanocytes thiab Keratinocytes (txo melanin hloov mus).
Suppressing Tyrosinase (tus nqi - txwv enzyme hauv melanin synthesis).
Cov Tshuaj Pleev Kom Zoo Nkauj: 2 - 5% (nyab xeeb rau kev siv ntev tom ntev). Pom kev txhim kho hauv cov pirmentation hauv pirmentation hauv pirmentation zog tsis pub dhau 8-12 lub lis piam ntawm kev siv txhua hnub.
Post -}} hyperpigmentation (PIH): Siv tau zoo rau kev txo pih los ntawm pob txuv, kub hnyiab, lossis kev kho mob laser. Cov ntaub ntawv thov nrawm nrawm nrawm los ntawm kev tsis txaus ntseeg, feem ntau ua ke nrog cov vitamin C lossis Niacinamide rau cov teebmeem kev cuam tshuam.
Kev Ua Tau Zoo & Kev Tsim Kho Kev Nyab Xeeb
Kev siv cov acid tranexamic
Cov Khoom Siv Raw & Synthesis: Tsim los ntawm catalytic hydrogenation ntawm para {{0} ineomethylbenzoic acid (Pamba) ua raws li los ntawm kev ua kom huv ntawm recrystallization. Cov ntaub ntawv nyoos ntsib USP / EP qauv rau impurity txwv (piv txwv li, Pamba tsawg dua lossis sib npaug ntawm cov tshuaj lom lossis ua xua.
Cov txheej txheem ntau lawm:
Kws Tshuaj Kho Mobile -} Cov Acid Tranexamic Acid yog ua tiav kev tswj hwm thiab cov chav kawm zaum kawg ua rau muaj kev sib dhos ua ke.
Cov tshuaj pleev kom zoo - Cov khoom lag luam qib ntxiv kom tshem tawm cov kab mob kev nyab xeeb (tsawg dua los yog sib npaug)- tsis zoo).
Kev Ntsuas Xyuas Cov Quav:
| Ntsuas Yam | Txojkev | Kev lees txais cov txheej txheem |
|---|---|---|
| Purity & Lwm Yam Tshuaj | HPLC (C18, 220 NM Nrhiav Kom Tau) | Kws tsim kho cov qib: ntau dua los yog sib npaug rau 99.0%, ib leeg impurity tsawg dua los yog sib luag rau 0.1%; Daim phiajcawv Qib: Ntau dua los yog sib npaug rau 98.0%, ib leeg impurity tsawg dua los yog sib luag rau 0.5% |
| PH nqi | Potentiometry (5% kev daws teeb meem) | 6.0-8.0 |
| Cov hlau hnyav | ICP - ms (inductively coupled ntshav -} cov spectrometry) | PB tsawg dua lossis sib npaug rau 10ppm, Hg tsawg dua lossis sib npaug ntawm 1PPM, Cd tsawg dua lossis sib npaug lossis sib npaug |
| Cov ntsiab lus chloride | Lub kaum (cov txheej txheem nitrate) | Tsawg dua los yog sib npaug rau 0.02% |
| Daim qhia npe | IR Spectroscopy & HPLC khaws sijhawm | Ntais ntawv siv cov qauv hluav taws xob thiab lub sijhawm khaws cia |
Kev Nyab Xeeb Kev Nyab Xeeb:Siv Khoom Siv:
Cov contraindications: hypersensitivity mus rau cov roj av tranexamic; Cov venous eromboembolism (VTE, piv txwv li, Vishle tob tob thrombosis, pulmonary embolism); Kev ua kom pom tseeb (Creatinine tshem tawm<30 mL/min).
Tsis tshua muaj kev phiv: lub plab zom mov tsis xis nyob (xeev siab, mob taub hau, thiab, nyob rau hauv ntev kev pheej hmoo {}}} Tshawb cov neeg mob ntawm thrombosis.
Kev Siv Cov Tshuaj Kho Mob:
Muaj kev nyab xeeb rau feem ntau hom tawv nqaij, tab sis thaj kev xeem yog pom zoo rau cov tawv nqaij rhiab (zam kev siv rau ntawm cov tawv nqaij tawg lossis tawv nqaij tawg).
Tsis yog cov duab, tab sis kev siv cov tshuaj pleev thaiv hnub qub (SPF loj dua los yog sib npaug rau 30) yog qhia kom tiv thaiv kom tsis txhob muaj peev xwm ntxiv.
Kev Koom Tes & Hu
Peb muab cov roj av tanexamic hauv cov kab mob tshuaj (rau cov ntsiav tshuaj ntawm qhov ncauj, IV txhaj tshuaj, thiab theem kev ua kom zoo nkauj (rau kev ua kom zoo nkauj). Peb muab cov khoom siv tau yooj yim:
R & D Cov qauv: 100g-1kg (rau cov qauv kev txhim kho thiab kev sim tshuaj).
Kev Lag Luam: 10KG-500kg ib qho kev txiav txim (Lub Peev Xwm Txhua Hli Ntawm 1000Kg).
Tus nqi -} muaj kev pabcuam ntxiv nrog:
Muab cov ntaub ntawv DMF (cov ntaub ntawv tshuaj) thiab CEP (Daim Ntawv Pov Thawj Ntawm Cov Khoom Siv) rau Cov Ntaub Ntawv Qib Los Pab Rau Cov Neeg Kawm Ntawv rau EU, Asmeskas, thiab Asia.
Customized particle size control (micronization for cosmetic serums) and aqueous solution preparation (for ready-to-use cosmetic bases).
KEV PAB TXHAWB KEV TXHAWB RAU KEV Tsim Kom Muaj Kev Ruaj Ntseg ruaj khov (piv txwv, tiv thaiv hydrolysis hauv cov ntawv ua kua).
Yog tias koj yog cov kws ua lag luam tshuaj, pleev xim, lossis tuam txhab kho mob, thov hu rau peb kom paub meej koom tes:
Cov ntaub ntawv tiv toj:
Tus email: {sales@huarongpharma.com
Xov tooj / WhatsApp: +86 13751168070
Peb ua raws li cov ntsiab cai ntawm "chaw muag tshuaj ua raws cai, kev nyab xeeb, thiab yeej}} {} {}} {} {}}}} Kev koom tes nrog ntiaj teb kev noj qab haus huv thiab kev lag luam zoo nkauj!
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