Flurbiprofen (CAS tsis muaj.: 5104 - 4}} 4) -} {4 3}} 4) -} Lom zem rau kev kho mob
Raws li tus kws tshaj lij kev lag luam ntawm cov chaw muag tshuaj - Cov Tshuaj Muaj Zog (NSAID}}}}} Cov Qauv PharopheoDo (USP, EP, BP, CP). Ib tug muaj zog prodic acid {{4} derived NSAID, thiab tswj hwm}}}}} tswj kev nyab xeeb kev nyab xeeb profertical rau ntau haiv neeg kuaj mob.
Cov Khoom Siv Khoom Siv Khoom
| Yam | Cov ntsiab lus |
|---|---|
| Khoom npe | Flurbiprofen |
| Cas Tsis tau. | 5104-49-4 |
| Txhais lus hais tias | (±) -2- (2-fluorobiphenyl-4-yl) propanoic acid; Fluobiprofen |
| Molecular Cov Qauv | C₁₅h₁₃fo₂ |
| Molecular hnyav | 244.26 |
| Kev tshwm sim | Dawb lossis yuav luag dawb crystalline hmoov; Odorless lossis nrog tus cwj pwm me ntsis tsw |
| Kev qhia tshwj xeeb | Kws tsim tawm ntawm kws tshuaj; Purity ntau dua los yog sib npaug rau 99.0% (HPLC); Poob rau ziab qis dua lossis sib npaug rau 0.5%; Residue ntawm ignition tsawg dua los yog sib npaug rau 0.1%; Cov hlau hnyav tsawg dua los yog sib npaug rau 10ppm; Ua raws li cov kuab tshuaj seem (piv txwv li, methanol, ethyl acetate) txwv |
Khoom Tseem Ceeb Ua Haujlwm & Kev Siv
Flurbiprofen exert ntawm nws cov teebmeem pharibermological los ntawm kev cuam tshuam cyclooxygenase (cox-2) - cov enzymes tseem ceeb nyob rau hauv synthesis ntawm prostaglandins (mob modiators (mob kho mob). Los ntawm kev txo cov qib prostaglandin, nws ua rau muaj mob, o, thiab ua npaws. Nws yog tshwj xeeb siv nyob rau hauvTib Neeg Kws Tshuaj(Tsis muaj cov neeg kho tsiaj thov) thoob plaws txoj kev tswj hwm:
1. Qhov ncauj tsim nyog (mob thiab kev tswj hwm caj dab)
Txiaj Ntsig Kev Mob: Kho kom haum rau cov menyuam yaus, mob Hniav
Mob mob caj dab: Ntev {- Lub sij hawm tswj ntawm rheumatoid mob caj dab, ncu kev sib koom ua ke o, thiab mob kom txhim kho kev mus ncig thiab lub neej zoo.
Ntse cov ntaub ntawv: Cov khoom siv raw rau ntawm qhov ncauj, tshuaj ntsiav, thiab txuas ntxiv {{tso tawm cov yeeb yam (kom txo qis kev ua kom ntshav).
2. Tsom xyeev formulations (hauv nruab nrab qhov mob)
Dermatological & cov leeg siv cov leeg siv: Tsim los rau hauv cream, gels, thiab thaj ua rau thaj rau cov mob hauv zos, xws li:
Osteoarthritis ntawm lub hauv caug, luj tshib, lossis tes (tsom pob sib koom tes ncaj qha).
Kev raug mob cov ntaub so ntswg (piv txwv li, mob ntsws, bursitis) thiab mob ib ce.
Qhov Tseem Ceeb: Cov ntaub ntawv thov kev nqus cov txheej txheem txo qis (txo cov plab zom zaws) thaum xa cov tshuaj ncaj qha rau ntawm qhov chaw mob.
3. Ophththalmic formulations (ocular o)
Post -} Cov Haujlwm Ocular Care: Qhov muag poob rau kev tshem tawm mob, o, thiab photophobia phais lossis rov phais mob siab (piv txwv li, lasik).
Tsis -} kis tau mob ocular: Kho cov Uterior Ueveitis thiab kev tsis haum thiab kev txo qis, edema, thiab tsis xis nyob ntxiv (tsis zoo li lwm yam NSAIDS).
Kev Ua Tau Zoo & Kev Tsim Kho Kev Nyab Xeeb
Raws li Nsaid nrog cov kev pheej hmoo noj qab haus huv thiab cov kev pheej hmoo plawv, Flurbiprofen yuav tsum tau tswj nruj kom ntseeg tau tias qhov ua tau zoo thiab kev nyab xeeb:
Cov Khoom Siv Raw Khoom Noj: Siv siab - Kev purity aromatic precursors (piv txwv li cov tshuaj lom neeg (piv txwv li cov khoom siv regiaisIr)
Cov txheej txheem ntau lawm: Tsim nyob rau hauv GMP - Daim ntawv ua haujlwm raug pom zoo, thiab cov txheej txheem nruj me ntsis), thiab cov txheej txheem kom huv si kom ntseeg tau tias cov khoom ruaj khov, sib dhos, thiab cov kev sib dhos zoo nkauj.
Kev Ntsuas Cov Quav: Txhua pob undergoes muaj kev soj ntsuam txhij txhua, suav nrog:
HPLC tsom xam rau kev coj dawb huv thiab cov khoom siv cuam tshuam (ib leeg impurity tsawg dua los yog sib luag rau 0.1%, tag nrho cov impurities tsawg dua los yog sib npaug rau 0.5%).
Melting taw tes txiav txim (114-117 degree).
Cov Hlau Hnyav (PB, HG, CD, CD) thiab Kev Kuaj Ntsuas Microbial (Tseem Ceeb rau Ophthalmic thiab Cov Qib Pos).
Assay rau qhov kho tau kho qhov muag (rau chairal formulations, raws li s- flurbiprofofen yog cov nquag enantiomer).
Kev Nyab Xeeb Kev Nyab Xeeb:
Kev pheej hmoo mob plab zom mov: Long-term oral use may cause ulcers or bleeding - avoid in patients with a history of peptic ulcers; Piav kev siv nrog cov tshuaj tiv thaiv kab mob tso tsis tau (PPIS) yog pom zoo kom txo qis kev pheej hmoo.
Kev Ceeb Toom Cardiovascular: Cov koob tshuaj ntau lossis lub sijhawm ntev yuav ua rau muaj kev pheej hmoo ntawm lub plawv dhia lossis mob stroke - siv cov tshuaj qis tshaj plaws rau lub sijhawm luv tshaj plaws.
Yam sib pauv: Hypersensitivity rau NSAIDS (piv txwv li, aspirin-}}}} lub kaum hli ntuj cev xeeb tub, thiab lub siab dua qub / hepatic tsis zoo.
Kev Koom Tes & Hu
Peb muab cov khoom siv ru cov ntaub ntawv sib xyaw rau cov khoom siv rau cov khoom siv thiab cov qauv tshuaj lom neeg, thiab o} Yog tias koj yog cov chaw ua lag luam kws saib xyuas, R & D yog cov kws xav tau cov khoom no, thov hu rau peb rau:
Cov ncauj lus kom ntxaws Pharmacopoeia Ua Raws Cov Ntaub Ntawv (piv txwv li, USP / EP Monograph Concoration).
Nqi, cov nyiaj cheb tshwj xeeb, thiab cov qauv thov.
Kev txhawb kev txhawb (piv txwv li, tsim kev sib txuam, chiral Purity Taus Lus).
Cov ntaub ntawv tiv toj:
Tus email: {sales@huarongpharma.com
Xov tooj / WhatsApp: +86 13751168070
Peb ua raws li cov ntsiab cai ntawm "Zoo ua ntej, tus neeg mob kev nyab xeeb kom tsim kev sib koom tes ntev nrog kev sib koom tes hauv ntiaj teb!
Hot Tags: Flurbiprofen, Flurbiprofen 5104 - 4 4}
Cim npe nrov: Flurbiprofen Cas # 5104-49-4, Tuam Tshoj Flurbiprofen Cas # 5104-49-4 Cov Chaw Tsim Tshuaj, cov chaw muag khoom
