Moxifloxacin Hydrochloride (CAS No.: 186826-86-}8) - Broad-Spectrum Quinolone Antibacterial API
Raws li tus kws tshaj lij kev lag luam ntawm cov kws tshuaj - qib tshuaj tua kab mob cov tshuaj tiv thaiv kab mob (APIs), peb muab Moxifloxacin Hydrochloride uas ua raws li cov qauv tshuaj tshuaj thoob ntiaj teb (USP, EP, CP). Ib tug thib plaub- tiam fluoroquinolone tshuaj tua kab mob, nws nthuav tawm dav -spectrum antimicrobial kev ua haujlwm tawm tsam Gram- cov kab mob zoo, Gram- cov kab mob tsis zoo, anaerobes, thiab cov kab mob atypical - ua rau nws yog cov tshuaj tseem ceeb rau kev kho cov kab mob hauv cov neeg laus.
Product Basic Information
| Yam khoom | Paub meej |
|---|---|
| Khoom npe | Moxifloxacin Hydrochloride |
| CAS Nr. | 186826-86-8 |
| Synonyms | Moxifloxacin HCl; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride |
| Molecular Formula | C₂₁H₂₅ClFN₃O₄ |
| Molecular Luj | 437.89 |
| Qhov tshwm sim | Lub teeb daj mus rau daj crystalline hmoov |
| Specification | Pharmaceutical qib; Purity Ntau dua lossis sib npaug li 99.0% (HPLC); Cov dej noo tsawg dua lossis sib npaug li 5%; Cov hlau hnyav tsawg dua lossis sib npaug li 20ppm |
| Melting Point | 324-325 degree |
| Boiling Point | 636℃(ntawm 760 mmHg) |
| Specific Optical Rotation | [ ]²⁵D -256℃(c=0.5, H₂O) |
| Kev cia khoom | Khaws kaw ntawm 2-8 degree, deb ntawm qhov chaw tshav kub, qhib nplaim taws, thiab cov tshuaj organic |
| Solubility | me ntsis soluble nyob rau hauv dej (soluble txog li 5mg / mL thaum rhuab, tsim ib tug ntshiab tov); Soluble hauv dimethyl sulfoxide (DMSO) |
Core Functions & Applications
Moxifloxacin Hydrochloride exerts nws cov tshuaj tua kab mob los ntawm inhibiting kab mob DNA gyrase (topoisomerase II) thiab topoisomerase IV-cov enzymes tseem ceeb koom nrog hauv cov kab mob DNA replication, kho, thiab transcription. Nws cov kab mob bactericidal yog concentration- nyob ntawm, thiab qhov tsawg kawg nkaus bactericidal concentration (MBC) yog qhov tseem ceeb raws li qhov tsawg kawg nkaus inhibitory concentration (MIC). Cov tshuaj no feem ntau yog siv los kho ntau yam kab mob tshwm sim los ntawm cov kab mob cuam tshuam rau cov neeg laus (Ntau dua lossis sib npaug rau 18 xyoo), nrog rau cov ntawv thov tshwj xeeb raws li hauv qab no:
1. Kev Kho Kab Mob Kab Mob (qhov ncauj / txhaj tshuaj)
Cov kab mob ua pa: Ua haujlwm ua ntej -kev kho kab mob rau zej zog- kis mob ntsws (CAP), mob ntsws mob ntsws ntev (AECB), thiab mob kab mob ntsws (ABS). Nws pom tau tias muaj txiaj ntsig zoo tiv thaiv kab mob los ntawmStreptococcus pneumoniae, Hemophilus influenzae, Klebsiella pneumoniae, lwm.
Daim tawv nqaij thiab cov ntaub so ntswg mos: Siv los kho tus mob nruab nrab- rau- mob hnyav ntawm daim tawv nqaij thiab cov nqaij mos uas tshwm sim los ntawm cov kab mob uas raug mob xws liStaphylococcus aureusthiab streptococci, suav nrog cellulitis thiab impetigo.
Lwm yam kab mob: Kuj tseem siv tau rau kev kho mob ntawm cov kab mob conjunctivitis, endocarditis, thiab tuberculosis (raws li ib feem ntawm kev sib xyaw ua ke hauv qee kis).
Daim ntawv noj tshuaj: Cov ntsiav tshuaj ntawm qhov ncauj (hloov ntau npaum li cas raws li hom kab mob) thiab cov tshuaj txhaj tshuaj (rau cov neeg mob tsis tuaj yeem noj cov tshuaj hauv qhov ncauj lossis muaj mob hnyav, siv los ntawm kev txhaj tshuaj intravenous).
2. Kev Kho Kab Mob Hauv Zos (Ophthalmic formulations)
Formulated rau hauv qhov muag tee rau kev kho cov kab mob conjunctivitis tshwm sim los ntawm cov kab mob raug. Cov thawj coj hauv cheeb tsam xa cov tshuaj ncaj qha mus rau qhov chaw kis kab mob, txo qis cov kab mob tsis zoo.
Quality & Safety Assurance
Raws li cov tshuaj noj, Moxifloxacin Hydrochloride yuav tsum muaj kev tswj xyuas nruj thiab kev siv tus qauv:
Raw Materials & Production: Synthesized siv high -purity intermediates. Cov txheej txheem tsim khoom yog ua nyob rau hauv GMP-cov kev cob qhia tau ntawv pov thawj, nrog kev tswj nruj ntawm cov tshuaj tiv thaiv, cov txheej txheem purification (xws li, kab chromatography), thiab cov txheej txheem crystallization kom paub meej cov khoom purity thiab stability. Txhua pawg ntawm cov khoom tau dhau los ua kev ntsuam xyuas, suav nrog HPLC purity tsom xam (ib qho impurity cov ntsiab lus ua raws li cov qauv tshuaj pharmacopoeia), nrhiav kom pom cov hlau hnyav, thiab kev txiav txim siab noo noo, kom ntseeg tau tias cov tshuaj muaj kev nyab xeeb.
Kev Tiv Thaiv Kev Nyab Xeeb:
Photosensitivity Risk: Ntev ntev thiab raug tshav ntuj los yog ultraviolet (UV) hluav taws xob thaum kho tej zaum yuav ua rau nruab nrab - mus rau - cov tshuaj tiv thaiv photosensitivity, xws li tawv nqaij kub hnyiab, hlwv, thiab erythema. Kev tiv thaiv tshav ntuj (xws li hnav looj tsom iav dub, siv tshuaj pleev thaiv hnub) yuav tsum tau noj thaum noj tshuaj. Tso tseg kev siv tam sim ntawd thiab nrhiav kev kho mob yog tias muaj teeb meem tshwm sim.
Antimicrobial Resistance: Txawm hais tias muaj txiaj ntsig zoo rau feem ntau cov tshuaj - cov kab mob resistant, nws yuav tsum tau siv nruj me ntsis raws li kws kho mob tau sau tseg kom tsis txhob muaj kev tsim txom thiab kev txhim kho cov tshuaj tiv thaiv.
Contraindications & ceev faj: Contraindicated nyob rau hauv cov neeg mob ua xua rau fluoroquinolone tshuaj; siv nrog ceev faj rau cov neeg mob uas muaj keeb kwm ntawm qaug dab peg lossis QT ncua ntev; tsis pom zoo rau cov poj niam cev xeeb tub, cov poj niam lactating, thiab cov menyuam yaus.
Kev koom tes & kev sib cuag
Peb muab tshuaj -qib Moxifloxacin Hydrochloride API, uas ua tau raws li cov kev xav tau ntawm ntau yam formulations xws li qhov ncauj, txhaj tshuaj, thiab tshuaj pleev. Peb muab cov kev pabcuam hloov pauv hloov pauv txij li gram- qib R & D cov qauv mus rau kilogram- qib xaj ntau. Yog hais tias koj yog ib tug kws lag luam, R & D lub koom haum, los yog formulation chaw tsim tshuaj paus, thov hu rau peb rau cov ncauj lus kom ntxaws specifications, pricing, bulk luv nqi, los yog technical support (xws li, formulation compatibility, stability kev taw qhia):
Cov ntaub ntawv tiv tauj:
Email: sales@huarongpharma.com
Xov tooj/WhatsApp: +86 13751168070
Peb ua raws li lub hauv paus ntsiab lus ntawm "kev ua tau zoo ua ntej, ua raws li kev ua haujlwm" thiab tos ntsoov yuav tsim kom muaj kev sib raug zoo ntev -, muaj txiaj ntsig kev sib raug zoo nrog cov neeg koom tes thoob ntiaj teb!
Hot Tags: Moxifloxacin Hydrochloride, 186826-86-8, Pharmaceutical Grade Moxifloxacin Hydrochloride, Broad-Spectrum Antibacterial Drug, Fluoroquinolone API, Respiratory Tract Infection Drug
Cim npe nrov: Tuam Tshoj Moxifloxacin Hydrochloride API CAS#186826-86-8, Tuam Tshoj Moxifloxacin Hydrochloride API CAS#186826-86-8 manufacturers, lwm tus neeg
