Gatifloxacin Mesylate CAS #316819-28-0

Gatifloxacin mesylate yog ib qho hluavtaws broad-spectrum antibacterial agent. Nws belongs rau tiam plaub ntawm fluoroquinolone tshuaj tua kab mob. Qhov sib xyaw no paub txog nws cov tshuaj tua kab mob muaj zog tiv thaiv ntau yam kab mob gram-zoo thiab gram-tsis zoo.

Gatifloxacin mesylate ua haujlwm los ntawm inhibiting cov haujlwm ntawm cov kab mob DNA gyrase thiab topoisomerase IV. Cov enzymes no yog qhov tseem ceeb rau cov kab mob DNA replication thiab transcription. Los ntawm inhibiting cov enzymes, gatifloxacin mesylate cuam tshuam cov kab mob DNA synthesis, ua rau cell tuag.

Cov txheej txheem ntawm kev ua no ua rau gatifloxacin mesylate zoo tiv thaiv ntau yam kab mob, suav nrog cov uas tiv taus lwm yam tshuaj tua kab mob. Nws muaj kev ua haujlwm tawm tsam cov kab mob xws li Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, thiab Streptococcus pneumoniae.

Tom qab kev tswj hwm qhov ncauj, gatifloxacin mesylate tau nqus sai sai los ntawm txoj hnyuv. Nws muaj bioavailability zoo, nrog kwv yees li 96% ntawm cov tshuaj tau nqus. Peak plasma concentrations mus txog hauv 1 mus rau 2 teev.

Cov tshuaj tau muab faib thoob plaws hauv lub cev, nrog rau kev ua tiav siab hauv cov ntaub so ntswg xws li ntsws, ob lub raum, prostate, thiab tawv nqaij. Nws tuaj yeem nkag mus rau hauv cov hlwb thiab mus txog qhov chaw kis kab mob, ua rau nws muaj txiaj ntsig zoo tiv thaiv kab mob hauv lub cev.

Gatifloxacin mesylate yog metabolized hauv daim siab los ntawm cytochrome P450 enzymes. Cov metabolite tseem ceeb yog desmethyl gatifloxacin, uas kuj muaj cov tshuaj tua kab mob. Cov tshuaj thiab nws cov metabolites raug tso tawm feem ntau hauv cov zis.

Gatifloxacin mesylate muaj txiaj ntsig zoo hauv kev kho mob ntawm cov kab mob ua pa xws li mob ntsws, mob ntsws, thiab sinusitis. Nws yog qhov tshwj xeeb tshaj yog nyob rau hauv cov neeg mob uas kis tau los ntawm cov kab mob uas tiv taus lwm yam tshuaj tua kab mob.

Nws kuj tseem siv tau los kho cov kab mob urinary, suav nrog cystitis thiab pyelonephritis. Cov tshuaj muaj ntau ntau nyob rau hauv lub raum thiab cov zis ua rau nws ib tug zoo kev xaiv rau cov kab mob no.

Gatifloxacin mesylate muaj nyob rau hauv ophthalmic formulations rau kev kho mob ntawm lub qhov muag kab mob xws li conjunctivitis thiab keratitis. Nws muaj kev nkag tau zoo rau hauv cov ntaub so ntswg qhov muag thiab muab kev ua haujlwm zoo los tiv thaiv kab mob.

Cov kab mob ntawm daim tawv nqaij thiab cov nqaij mos: Nws tuaj yeem siv los kho cov tawv nqaij thiab cov nqaij mos xws li cellulitis, abscesses, thiab qhov txhab mob. Kev ua haujlwm dav dav ntawm gatifloxacin mesylate ua rau nws muaj txiaj ntsig zoo tiv thaiv ntau yam kab mob uas tuaj yeem ua rau cov kab mob no.

Cov kev mob tshwm sim feem ntau muaj xws li xeev siab, ntuav, raws plab, mob taub hau, thiab kiv taub hau. Tsawg dua tab sis muaj kev phiv loj tuaj yeem tshwm sim, xws li cov leeg pob txha tawg, hypoglycemia, thiab QT ntev.

Tendon rupture yog ib qho tsis tshua muaj tab sis muaj teeb meem loj uas tuaj yeem tshwm sim nrog cov tshuaj tua kab mob fluoroquinolone. Nws muaj feem ntau tshwm sim hauv cov neeg mob laus, cov neeg noj corticosteroids, thiab cov neeg uas muaj keeb kwm ntawm cov leeg mob. Hypoglycemia tuaj yeem tshwm sim hauv cov neeg mob ntshav qab zib uas noj gatifloxacin mesylate, tshwj xeeb tshaj yog cov neeg noj cov tshuaj hypoglycemic ntawm qhov ncauj. QT ncua sij hawm tuaj yeem ua rau mob plawv mob hnyav thiab yog ib qho kev txhawj xeeb rau cov neeg mob uas muaj kab mob hauv lub plawv lossis cov neeg noj lwm cov tshuaj uas tuaj yeem ncua QT lub sijhawm.

Q1. Kuv puas tuaj yeem tau txais qee qhov qauv?

A1. Yog lawm, peb tuaj yeem muab cov qauv dawb, tab sis tus nqi thauj khoom yuav them los ntawm peb cov neeg siv khoom.

Q2. Yuav pib xaj lossis them nyiaj li cas?

A2. Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj. Kev them nyiaj peb tuaj yeem txais T / T, LC lossis DP.

Q3. Yuav ua li cas kom paub meej cov khoom zoo ua ntej muab xaj?

A3. Peb yuav muab COA rau koj daim tshev lossis xa cov qauv rau kev kuaj.

Q4. Koj qhov ntim ntim yog dab tsi?

A4. peb cov khoom ntim tsis tu ncua yog 25kg / nruas.

Q5. Yuav ua li cas txog shipping lub sij hawm?

A5. Txhawm rau npaj cov khoom thauj, peb tuaj yeem npaj xa cov khoom thauj sai li sai tau thaum tau txais cov nyiaj them poob haujlwm. Yog tias tsis muaj Tshuag, qhov ntau lawm yuav siv sijhawm 2-3 lis piam.

Q6. Puas muaj luv nqi?

A6. Peb muab tus nqi zoo dua rau qhov ntau dua.

q7 ua. Koj kho qhov kev tsis txaus siab zoo li cas?

A7. Ua ntej tshaj plaws, peb qhov kev tswj xyuas zoo yuav txo qhov teeb meem zoo kom ze rau xoom. Yog tias muaj teeb meem zoo tiag tiag los ntawm peb, peb yuav xa cov khoom dawb rau koj los hloov lossis rov qab koj cov nyiaj poob.

Q8. Yuav tiv tauj peb li cas?

A8. Koj tuaj yeem xaiv koj cov khoom txaus siab thiab xa lus nug rau peb ntawm eric@huarongpharma.com.

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